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Index > Protein center > CAMK2A(Gene name) > Human
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  • CAMK2A (Gene name),
  • Calcium/calmodulin-dependent protein kinase type II subunit alpha (Protein name ),  KCC2A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CAMK2A(CAMKA;KIAA0968);
    Protein name:
    Calcium/calmodulin-dependent protein kinase type II subunit alpha(CaM kinase II subunit alpha;CaMK-II subunit alpha);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with BAALC, MPDZ, SYN1, CAMK2N2 and SYNGAP1.
    Function:
    CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
    Subcellular Location:
    Cell junction synapse presynaptic cell membrane Cell junction synapse Postsynaptic lipid rafts.
    Protein Attributes:
    Sequence length:
    478
    Sequence:
    50:
    MATITCTRFT | EEYQLFEELG | KGAFSVVRRC | VKVLAGQEYA | AKIINTKKLS | 
    100:
    ARDHQKLERE | ARICRLLKHP | NIVRLHDSIS | EEGHHYLIFD | LVTGGELFED | 
    150:
    IVAREYYSEA | DASHCIQQIL | EAVLHCHQMG | VVHRDLKPEN | LLLASKLKGA | 
    200:
    AVKLADFGLA | IEVEGEQQAW | FGFAGTPGYL | SPEVLRKDPY | GKPVDLWACG | 
    250:
    VILYILLVGY | PPFWDEDQHR | LYQQIKAGAY | DFPSPEWDTV | TPEAKDLINK | 
    300:
    MLTINPSKRI | TAAEALKHPW | ISHRSTVASC | MHRQETVDCL | KKFNARRKLK | 
    350:
    GAILTTMLAT | RNFSGGKSGG | NKKSDGVKES | SESTNTTIED | EDTKVRKQEI | 
    400:
    IKVTEQLIEA | ISNGDFESYT | KMCDPGMTAF | EPEALGNLVE | GLDFHRFYFE | 
    450:
    NLWSRNSKPV | HTTILNPHIH | LMGDESACIA | YIRITQYLDA | GGIPRTAQSE | 
    478:
    ETRVWHRRDG | KWQIVHFHRS | GAPSVLPH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    SMR:
    String:
    KEGG:
    UniGene:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human CaM kinase II subunit alpha
    Cat.:
    E0655h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human CaM kinase II subunit alpha
    Cat.:
    E0655r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human CaM kinase II subunit alpha
    Cat.:
    E0655m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human CaM kinase II subunit alpha
    Cat.:
    U0655r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human CaM kinase II subunit alpha
    Cat.:
    U0655h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human CaM kinase II subunit alpha
    Cat.:
    U0655m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human CaM kinase II subunit alpha
    Cat.:
    P0655Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human CaM kinase II subunit alpha
    Cat.:
    P0655Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human CaM kinase II subunit alpha
    Cat.:
    P0655Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human CaM kinase II subunit alpha
    Monoclonal Antibody for Human CaM kinase II subunit alpha
    Monoclonal Antibody for Human CaM kinase II subunit alpha
    Protein for Human CaM kinase II subunit alpha
    Protein for Human CaM kinase II subunit alpha
    Protein for Human CaM kinase II subunit alpha

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human calcium/calmodulin-dependent protein kinase II: cDNA cloning and gene analysis."
      Li G.Y. , Cooper N.G.F.
      Submitted (1999-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A AND B)
      tissue: Brain.
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    3. 4.
      "SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation."
      Krapivinsky G. , Medina I. , Krapivinsky L. , Gapon S. , Clapham D.E.
      Neuron43:563-574(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MPDZ
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